Mary Tyler Moore Vision Initiative

MTM Vision Fall 2024 Symposium | Summation and Next Steps

  • Lloyd Paul Aiello MD, PhD  Professor of Ophthalmology, Joslin Diabetes Center, Harvard Medical School
  • S. Robert Levine, MD  Founder and CEO, MTM Vision Initiative

MTM Vision Fall 2024 Symposium | Communications, Collaborations and Fund Development

Moderator: Eric Carlson  Founder, The Carlson Company, Social Impact & Media, Award Winning Documentary and Film Producer: Public outreach, media relations, and fund development  

Panelists

  • Betsy Cote Joslin Diabetes Center
  • Chris Shoemaker  University of Michigan
  • Maurine Slutzky  Stand Up to Cancer
  • Sandy Puczynski, PhD  MTM Vision Lay Advisor

MTM Vision Fall 2024 Symposium | Consortium and Boehringer Ingelheim Collaboration

  • Shelby Unsworth, PhD  Associate Director, Business Development, Michigan Medicine
  • Marianne Laouri, PhD  Global Asset Lead, Retinal Health, Boehringer Ingelheim Pharmaceuticals

MTM Vision Fall 2024 Symposium | Special Guests

Will Flanary, MD and Kristin Flanary, MA – aka “Dr. Glaucomflecken” and “Lady Glaucomflecken.” 

Will and Kristin Flanary share how their medical experiences led to the creation of their personas as Dr and Lady Glaucomflecken and their resulting advocacy work in eye health and co-survivorship, blending humor and education to raise awareness and promote change.

MTM Vision Fall 2024 Symposium | Future Directions

Moderator: Mark Pennesi, MD, PhD Professor of Ophthalmology, School of Medicine, Oregon Health & Science University; Director, Ophthalmic Genetics at the Retina Foundation

Perspectives 

  • Rebecca Pfeiffer, PhD  Research Assistant Professor, Ophthalmology & Visual Science, John A. Moran Eye Center, University of Utah: Pathoconnectomics: Rewiring in Retinitis Pigmentosa.
  • Rachel Huckfeldt, MD, PhD  Assistant Professor of Ophthalmology, Harvard Medical School, Fellowship Director, Inherited Retinal Degenerations Fellowship, Mass Eye & Ear: How has the consortium helped the field of IRDs and the importance to discovery of natural history studies which incorporate functional markers and endpoints.

Panelists 

  • James Weiland, PhD  University of Michigan
  • Adriana Plevniak  MTM Vision Lay Advisor

MTM Vision Fall 2024 Symposium | Hot Topics

Facilitator: Chris German, PhD  Chair, MTM Vision Lay Advisory Committee

Perspectives

  • Awareness Crisis in DRDPaolo Silva, MD Associate Professor of Ophthalmology, Joslin Diabetes Center, Harvard Medical School:
  • Gait Assessment in the Evaluation of Functional Vision: Amanda Bicket, MD Assistant Professor, Ophthalmology and Visual Sciences, University of Michigan
  • Developing a Patient-Reported Outcome (PRO) for DRD – Creating tools to capture patient voicesFernanda (Maria) Abalem, MD, MSC, PhD  Faculty, University of Sao Paulo, Brazil
  • Vitreous analysis for clinical assessment, staging, and patient selection for clinical trialsJeffrey M. Sundstrom, MD, PhD  Associate Professor, Department of Cellular and Molecular Physiology, Neural and Behavioral Science, and Ophthalmology, Penn State University

MTM Vision Fall 2024 Symposium | Big Data and AI Approaches to Diabetic Retinal Disease

MTM Vision Update: S. Robert Levine, MD  Founder and CEO, MTM Vision

Perspectives 

  • Tien-en Tan, MBBS(Hons), MMed(Ophth), FRCOphth, FAMS  Clinical Assistant Professor, SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Program. Multi-modal AI for enhanced diagnosis, risk stratification and prognostication in DRD.
  • Brian VanderBeek, MD, MPH, MSCE  Research to Prevent Blindness (RPB)-MTM Vision Physician Scientist Award Winner; Associate Professor of Ophthalmology, University of Pennsylvania. Use of real-world data for better understanding of DRD and population-level differences.

Panelists 

  • Chris German, PhD Chair, MTM Vision Lay Advisory Committee
  • Kerry Goetz, PhD National Eye Institute
  • Tunde Peto, MD, PhD Queens University Belfast

MTM Vision Fall 2024 Symposium | Therapeutics Target Identification Through Human Tissue and Fluid ‘Omics

MTM Vision Update:  Patrice Fort, PhD  Director, MTM Vision Ocular Biorepository & Resource Center

Perspectives

  • Roger Cone, PhD  Mary Sue Coleman Director & Research Professor; Vice Provost and Director, U-M Life Sciences Institute; Professor, Department of Molecular & Integrative Physiology, U-M Medical School; Professor, Molecular, Cellular, and Developmental Biology, LSA. Process and resources for target identification and drug development.
  • Przemyslaw (Mike) Sapieha, PhD  Founder & Chief Scientific Officer, SemaThera Inc. From target identification to drug development for ocular diseases.

Panelists

  • Lloyd Paul Aiello, MD, PhD  Harvard Medical School
  • Eric Ng, PhD | Eyebiotech Limited, a subsidiary of Merck & Co, Inc (Rahway, NJ)
  • Subramaniam Pennathur, MD University of Michigan
  • Judy Hunt, MBA MTM Vision Lay Advisor

MTM Vision Fall 2024 Symposium | Translating Science to Clinical Care for Diabetic Retinal Disease

MTM Vision Update:  Jennifer Sun, MD, MPH  Science Co-Director, MTM Vision

Perspectives

  • Aude Couturier, MD PhD Professor of Ophthalmology, Paris Cité University; Deputy Head of the Ophthalmology Department, Lariboisière and Saint-Louis University Hospitals; Project leader EviRED (Evaluation Intelligente de la Rétinopathie Diabétique). Preliminary findings from EviRED natural history study. 
  • Malvina Eydelman, MD Director of the Office of Health Technology Ophthalmic, Anesthesia, Respiratory, ENT and Dental Devices, Office of Product Evaluation and Quality, Food and Drug Administration, Maryland, USA. Food and Drug Administration Regulation of Medical Products for DRD 

Panelists

  • Michael Abramoff, MD, PhD University of Iowa 
  • Jason McAnany, PhD University of Illinois College of Medicine 
  • Sandy Puczynski, PhD  MTM Vision Lay Advisor 

Boehringer Ingelheim Joins the Mary Tyler Moore Vision Initiative to Combat Vision Loss From Diabetes

Boehringer Ingelheim announces partnership with Mary Tyler Moore Vision Initiative to target diabetic retinal disease – November 12, 2024

November 15, 2024

By Sydney M Crago

This announcement establishes Boehringer as the first pharmaceutical company to join the MTM Vision Consortium.

Boehringer Ingelheim and the Mary Tyler Moore Vision Initiative (MTM Vision) have begun what is expected to be a long-term collaboration. This announcement establishes Boehringer as the first pharmaceutical company to join the MTM Vision Consortium.

The MTM Vision Consortium

The MTM Vision Consortium is working to unite innovators in the pre-competitive space from universities, foundations, as well as pharmaceutical and biotech companies. The consortium is housed at the University of Michigan. It hopes to lead international collaboration and is motivated by the urgency of millions of people worldwide who have lost or are at risk of losing their eyesight as a consequence of diabetes.1

The Consortium members share several goals:

  • address the need for novel means to better diagnose and stage diabetic retinal diseases (DRDs)
  • validate promising clinical trial endpoints and biomarkers, and
  • accelerate the development of breakthrough therapies.

With these goals in mind, there is potential for treatment earlier in disease, before vision loss occurs, and to contribute to the creation of new regulatory pathways for drug approval.1

A new collaboration

Dr. Ulrike Graefe-Mody, Global Head of Retinal Health at Boehringer Ingelheim is quoted in the joint press release1 as saying, “We are excited to join forces with MTM Vision in leading a new era of vision preservation and protection for people living with diabetes. This collaboration will help us enhance our understanding of the progression of diabetic retinopathy and the role of retinal non-perfusion, supporting the development of our portfolio in diabetic retinal diseases. It also gives us access to a unique biospecimen bank, accelerating our research and biomarker identification. In return, we are openly sharing our current efforts for evidence generation to further understand DRD and support MTM Vision’s work. Together, we are setting a course to fundamentally change our understanding of vision loss from diabetes and how it is treated.”

Dr. S. Robert Levine, founder and CEO of MTM Vision provided an update on the news around the consortium, saying, “Here at our third Annual Global Symposium on curing vision loss from diabetes, which coincides with Diabetic Eye Disease Awareness Month, we are delighted to announce that Boehringer Ingelheim has joined us as a founding member of our MTM Vision Consortium. This Symposium provides a platform for the convening of global leaders dedicated to accelerating the development of innovative therapies to prevent and cure vision loss from diabetes. Boehringer Ingelheim’s commitment to our pre-competitive Consortium marks a pivotal moment along our path to ensure better patient outcomes by advancing research and sharing critical data. This will significantly strengthen our efforts to catalyze the development of new methods to diagnose and treat diabetic retinal disease earlier, which may preserve vision for millions of people at risk.”1

Reference:
1. Boehringer Ingelheim and the Mary Tyler Moore Vision Initiative join forces to combat vision loss from diabetes. Mary Tyler Moore Vision Initiative/Boehringer Ingelheim. November 12, 2024. Accessed November 15, 2024. https://www.globenewswire.com/news-release/2024/11/12/2978779/0/en/Boehringer-Ingelheim-and-the-Mary-Tyler-Moore-Vision-Initiative-join-forces-to-combat-vision-loss-from-diabetes.html
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